Issues

• Designing a symmetric binder

  RosettaCommons/RFdiffusion#456 · Filter by author chiarinival-dot opened on Jun 8, 2026
  3

• Two-sided partial diffusion with sequence gaps?

  RosettaCommons/RFdiffusion#453 · Filter by author dennisbrookner opened on May 18, 2026
  1

• RF diffusion colab- RMSD

  RosettaCommons/RFdiffusion#449 · Filter by author protein-3dwork opened on Apr 3, 2026

• 5070Ti cuda error

  RosettaCommons/RFdiffusion#444 · Filter by author Lucky-xf opened on Mar 17, 2026
  6

• Deformation of coordinate space

  question
  RosettaCommons/RFdiffusion#443 · Filter by author victorvinsmoke opened on Feb 24, 2026

• Job crash (Segmentation fault) during run

  RosettaCommons/RFdiffusion#442 · Filter by author henryyeung-deb opened on Feb 20, 2026

• Contradiction between RFD3 design and AF3 prediction

  question
  RosettaCommons/RFdiffusion#440 · Filter by author nmbiss747-netizen opened on Jan 27, 2026
  3

• How to make it work properly on CUDA 13 with an RTX 5090?

  RosettaCommons/RFdiffusion#439 · Filter by author bioinformatica opened on Jan 14, 2026
  1

• The Colab notebook

  RosettaCommons/RFdiffusion#438 · Filter by author Jameel9 opened on Jan 9, 2026
  2

• Numpy problem when running with Docker

  RosettaCommons/RFdiffusion#435 · Filter by author dtenenba opened on Dec 12, 2025
  3

  

• The cyclic peptides generated by RFdiffusion are not closed.

  RosettaCommons/RFdiffusion#434 · Filter by author zunyi-zhang opened on Dec 8, 2025
  1

• Error: Multiple chain IDs in chain: {'A', 'B'}

  RosettaCommons/RFdiffusion#432 · Filter by author DrLeucine opened on Dec 6, 2025
  

• Primary config directory not found.

  RosettaCommons/RFdiffusion#431 · Filter by author dhiraj82 opened on Dec 3, 2025
  6

  

• With symmetry, Hydra throws minor warning

  RosettaCommons/RFdiffusion#427 · Filter by author TristynAlxander opened on Nov 23, 2025

• Seeking guidance on hotspot specification and unexpected results

  RosettaCommons/RFdiffusion#423 · Filter by author schoyeon opened on Nov 18, 2025
  2

• outdated requirements, how to install on cuda 12.x and python 3.11 or later ?

  RosettaCommons/RFdiffusion#422 · Filter by author schloegl opened on Nov 17, 2025
  1

• Installation support for Windows / WSL users (CUDA, DGL, cu117 issues)

  RosettaCommons/RFdiffusion#421 · Filter by author 8MaCaVeL8 opened on Nov 13, 2025
  1

• How to generate multiple helices instead of one long helix when extending a protein backbone with RFdiffusion？

  RosettaCommons/RFdiffusion#414 · Filter by author WHUminghui opened on Oct 23, 2025
  3

• AME Benchmark Clarification

  RosettaCommons/RFdiffusion#412 · Filter by author ghost opened on Oct 18, 2025
  2

• Cannot install RFDiffusion on VM with X86-64, pytorch_cuda-12.8.1, RTX 5090 GPU

  RosettaCommons/RFdiffusion#411 · Filter by author biocatchen opened on Oct 17, 2025
  4

• AttributeError: 'SelfConditioning' object has no attribute 'idx_pdb'

  RosettaCommons/RFdiffusion#408 · Filter by author mxue316 opened on Sep 28, 2025
  2

• Cyclic peptide design issues

  RosettaCommons/RFdiffusion#406 · Filter by author zzxchelly opened on Sep 27, 2025
  2

• Question: RFpeptides Branch - Should I clone the branch directly or merge with main for containerization?

  RosettaCommons/RFdiffusion#405 · Filter by author BiologyGeek opened on Sep 26, 2025
  3

• Missing sidechain of target in output

  RosettaCommons/RFdiffusion#403 · Filter by author DazLe-Q opened on Sep 23, 2025
  6

• Cyclic peptide structure prediction

  RosettaCommons/RFdiffusion#401 · Filter by author AzusaXuan opened on Sep 16, 2025
  1