diff --git a/tools/base/requirements.txt b/tools/base/requirements.txt
index 63cc39a1b0098..853c9df330182 100644
--- a/tools/base/requirements.txt
+++ b/tools/base/requirements.txt
@@ -1747,7 +1747,7 @@ zstandard==0.23.0 \
     # via envoy-base-utils
 
 # The following packages are considered to be unsafe in a requirements file:
-setuptools==75.6.0 \
-    --hash=sha256:8199222558df7c86216af4f84c30e9b34a61d8ba19366cc914424cdbd28252f6 \
-    --hash=sha256:ce74b49e8f7110f9bf04883b730f4765b774ef3ef28f722cce7c273d253aaf7d
+setuptools==78.1.0 \
+    --hash=sha256:18fd474d4a82a5f83dac888df697af65afa82dec7323d09c3e37d1f14288da54 \
+    --hash=sha256:3e386e96793c8702ae83d17b853fb93d3e09ef82ec62722e61da5cd22376dcd8
     # via -r requirements.in