diff --git a/master/custom/builders.py b/master/custom/builders.py
index 20b9a400..a2012f0b 100644
--- a/master/custom/builders.py
+++ b/master/custom/builders.py
@@ -41,6 +41,8 @@
     RHEL8NoBuiltinHashesUnixBuildExceptBlake2,
     CentOS9NoBuiltinHashesUnixBuild,
     CentOS9NoBuiltinHashesUnixBuildExceptBlake2,
+    CentOS10NoBuiltinHashesUnixBuild,
+    CentOS10NoBuiltinHashesUnixBuildExceptBlake2,
     Windows64Build,
     Windows64NoGilBuild,
     Windows64PGOTailcallBuild,
@@ -400,6 +402,12 @@ def generate_builderdefs(tags, entries):
     ("AMD64 Fedora Rawhide LTO", "cstratak-fedora-rawhide-x86_64", LTONonDebugUnixBuild),
     ("AMD64 Fedora Rawhide LTO + PGO", "cstratak-fedora-rawhide-x86_64", LTOPGONonDebugBuild),
 
+    # CentOS Stream 10 Linux x86-64 GCC
+    ("AMD64 CentOS10", "cstratak-CentOS10-x86_64", CentOS10Build),
+    ("AMD64 CentOS10 Refleaks", "cstratak-CentOS10-x86_64", UnixRefleakBuild),
+    ("AMD64 CentOS10 LTO", "cstratak-CentOS10-x86_64", LTONonDebugUnixBuild),
+    ("AMD64 CentOS10 LTO + PGO", "cstratak-CentOS10-x86_64", LTOPGONonDebugBuild),
+
     ("AMD64 Ubuntu", "skumaran-ubuntu-x86_64", UnixBuild),
 
     ("AMD64 RHEL8 FIPS No Builtin Hashes", "cstratak-RHEL8-fips-x86_64", RHEL8NoBuiltinHashesUnixBuild),
@@ -407,6 +415,9 @@ def generate_builderdefs(tags, entries):
     ("AMD64 CentOS9 FIPS Only Blake2 Builtin Hash", "cstratak-CentOS9-fips-x86_64", CentOS9NoBuiltinHashesUnixBuildExceptBlake2),
     ("AMD64 CentOS9 FIPS No Builtin Hashes", "cstratak-CentOS9-fips-x86_64", CentOS9NoBuiltinHashesUnixBuild),
 
+    ("AMD64 CentOS10 FIPS Only Blake2 Builtin Hash", "cstratak-CentOS10-fips-x86_64", CentOS10NoBuiltinHashesUnixBuildExceptBlake2),
+    ("AMD64 CentOS10 FIPS No Builtin Hashes", "cstratak-CentOS10-fips-x86_64", CentOS10NoBuiltinHashesUnixBuild),
+
     BuilderDef(
         "AMD64 Arch Linux Valgrind",
         ValgrindBuild,
@@ -425,6 +436,10 @@ def generate_builderdefs(tags, entries):
     ("AMD64 Fedora Rawhide Clang", "cstratak-fedora-rawhide-x86_64", ClangUnixBuild),
     ("AMD64 Fedora Rawhide Clang Installed", "cstratak-fedora-rawhide-x86_64", ClangUnixInstalledBuild),
 
+    # CentOS Stream 10 Linux x86-64 Clang
+    ("AMD64 CentOS10 Clang", "cstratak-CentOS10-x86_64", ClangUnixBuild),
+    ("AMD64 CentOS10 Clang Installed", "cstratak-CentOS10-x86_64", ClangUnixInstalledBuild),
+
     # Fedora Linux ppc64le GCC
     # Fedora Rawhide is unstable
     ("PPC64LE Fedora Rawhide", "cstratak-fedora-rawhide-ppc64le", FedoraRawhideBuild),
diff --git a/master/custom/factories.py b/master/custom/factories.py
index 8e56cbeb..9fa1b28d 100644
--- a/master/custom/factories.py
+++ b/master/custom/factories.py
@@ -557,6 +557,24 @@ class CentOS9NoBuiltinHashesUnixBuild(CentOS9Build):
     factory_tags = ["no-builtin-hashes"]
 
 
+class CentOS10NoBuiltinHashesUnixBuildExceptBlake2(CentOS10Build):
+    # Build on 64-bit CentOS Stream 10 using: --with-builtin-hashlib-hashes=blake2
+    buildersuffix = ".no-builtin-hashes-except-blake2"
+    configureFlags = CentOS10Build.configureFlags + [
+        "--with-builtin-hashlib-hashes=blake2"
+    ]
+    factory_tags = ["no-builtin-hashes-except-blake2"]
+
+
+class CentOS10NoBuiltinHashesUnixBuild(CentOS10Build):
+    # Build on 64-bit CentOS Stream 10 using: --without-builtin-hashlib-hashes
+    buildersuffix = ".no-builtin-hashes"
+    configureFlags = CentOS10Build.configureFlags + [
+        "--without-builtin-hashlib-hashes"
+    ]
+    factory_tags = ["no-builtin-hashes"]
+
+
 ##############################################################################
 ############################  MACOS BUILDS  ##################################
 ##############################################################################
diff --git a/master/custom/workers.py b/master/custom/workers.py
index a68b5244..fe089024 100644
--- a/master/custom/workers.py
+++ b/master/custom/workers.py
@@ -144,6 +144,18 @@ def get_workers(settings):
             # Only 3.12+ for FIPS builder
             branches=BRANCHES.only_since(3, 12),
         ),
+        cpw(
+            name="cstratak-CentOS10-x86_64",
+            tags=['linux', 'unix', 'rhel', 'amd64', 'x86-64', 'dtrace'],
+            parallel_tests=6,
+        ),
+        cpw(
+            name="cstratak-CentOS10-fips-x86_64",
+            tags=['linux', 'unix', 'rhel', 'amd64', 'x86-64', 'fips', 'dtrace'],
+            parallel_tests=6,
+            # Only 3.12+ for FIPS builder
+            branches=BRANCHES.only_since(3, 12),
+        ),
         cpw(
             name="cstratak-fedora-rawhide-ppc64le",
             tags=['linux', 'unix', 'fedora', 'ppc64le', 'dtrace'],