In our stack where we want to use the python client we currently have cryptography in version 46.0.3. The current version in pyproject.toml is < 45.0, which restricts to 44.0.3, which has been released in May 2025. Studying the changelog of cryptography I have not seen any entries that would prevent the python client from using a newer version.
This is also part of the latest "uv-version-updates" dependabot PR but I don't know what your plans are with those.
We wouldn't be able to use the python-client without this version bump so I kindly ask you to update it for the next (or one of the next) beta releases.