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Point INTERVIEW→GALAXY scenarios at gap-closing reference workflows#319

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jmchilton merged 1 commit into
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interview-galaxy-scenario-references
Jun 17, 2026
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Point INTERVIEW→GALAXY scenarios at gap-closing reference workflows#319
jmchilton merged 1 commit into
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interview-galaxy-scenario-references

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Posted by Claude (AI assistant) on behalf of jmchilton.

Both INTERVIEW → GALAXY scenario targets were deliberately known-incomplete extractions. This swaps each for the iterated workflow that closes its catalogued gap, and loosens the WIP hedging accordingly.

What changed

UC1 / MRSAUC1_MRSA_extracted.ga (14-step) → UC1_MRSA_Bakta_JBrowse_faithful.ga (35-step).

  • The docs name this "the definitive artifact … re-runs byte-identical to golden." clean_extract is explicitly superseded (structurally clean but map→reduce unfaithful); extracted is the earliest.
  • Integrates Bakta whole-genome annotation + per-isolate JBrowse locus view — the two deliverables the old target dropped. Six __BUILD_LIST__ nests keep every mapped multiple-input (staramr, both closest joins, three JBrowse tracks) from silently reducing.
  • Note: this diverges from the paper SI, which kept the clean 14-step S1 as its published baseline. Chosen as a richer compare reference.

UC3 / ATACUC3_ATAC_extracted.ga (5-step) → UC3_ATAC_extracted_figures.ga (13-step, paper SI Workflow S5).

  • Materializes the significance filter → SortSelect first/Select last (top-gained / top-lost) ranked tables as real workflow outputs, instead of trapping the differential call inside the volcano PDF's coloring.

Hedging loosened in scenarios.md + issue headers

  • Dropped "not human-validated", "known-incomplete by design / they aren't good enough yet", and both per-case "known limitation (bonus points to beat it)" blocks.
  • Kept the deliberate "compare-and-contrast reference, not a hard oracle / divergence is the signal" stance — that's design intent, not WIP hedging.
  • Removed the two now-obsolete UC*_NEXT_STEPS.md gap-handoff notes.

Validation

npm run validate → 0 errors (172 pre-existing warnings, none in this pipeline).

🤖 Generated with Claude Code

Both scenario targets were known-incomplete extractions. Swap each for the
iterated workflow that closes its catalogued gap, and loosen the WIP hedging.

UC1 MRSA: 14-step extract -> UC1_MRSA_Bakta_JBrowse_faithful.ga (35-step,
the definitive faithful artifact; 6 __BUILD_LIST__ nests keep every mapped
multiple-input from reducing). Integrates Bakta annotation + per-isolate
JBrowse locus view -- the two deliverables the old target dropped.

UC3 ATAC: 5-step extract -> UC3_ATAC_extracted_figures.ga (13-step, paper
SI Workflow S5). Materializes the significance filter -> Sort -> top-gained/
top-lost ranked tables as real outputs instead of trapping the call in the
volcano PDF.

Drop "not human-validated", "known-incomplete by design", and both per-case
"known limitation" blocks; keep the deliberate compare-reference (not hard
oracle) stance. Remove the now-obsolete UC*_NEXT_STEPS.md gap handoffs.

Co-Authored-By: Claude Opus 4.8 (1M context) <noreply@anthropic.com>
@jmchilton jmchilton merged commit 9620899 into main Jun 17, 2026
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@jmchilton jmchilton deleted the interview-galaxy-scenario-references branch June 17, 2026 21:51
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