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@omicverse

omicverse

Building interoperable open-source tools for next-generation omics data analysis.

omicverse

Welcome to omicverse!

omicverse is a community-built open-source ecosystem for omics data analysis in Python — from foundational I/O and reimagined algorithms to end-user interfaces. Everything you see below is open to contribution, whether you bring a new algorithm, a tutorial, or a port of an R package.

Architecture

                                                      omicverse
                                                          │
              ┌─────────────────────────┬─────────────────┴─────────────┬────────────────────────────────┐
            Tools                   Tutorials                      Algorithms                       Foundations
              │                         │                               │                                │
        ┌─────┴─────┐            ┌──────┴──────┐           ┌────────────┼─────────────┐                  │
        │           │            │             │           │            │             │                  │
   omicverse-   omicclaw   single_cell_      your      In-house    Integrated     R bridges         anndata-oom
    notebook                 tutorial      tutorial
                                            welcome                                   │
                                                                               ┌──────┴──────┐
                                                                               │             │
                                                                          py-monocle2   py-CellChat
                                                                                         (planned)

In-house · original ML / DL methods — contributions welcome  |  Integrated · best-in-class methods unified under one API

Here's how to get started:

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  1. omicverse omicverse Public

    A python library for multi omics included bulk, single cell and spatial RNA-seq analysis.

    Python 1.2k 147

  2. anndata-oom anndata-oom Public

    Out-of-memory AnnData powered by Rust — a drop-in replacement for anndata.AnnData that keeps the expression matrix on disk and runs entire preprocessing pipelines

    Jupyter Notebook 10 1

  3. omicverse-notebook omicverse-notebook Public

    JupyterLab plugin that brings the omicverse-web DataFrame and AnnData preview ideas into a standalone package.

    CSS 1 1

  4. omicverse-rebuildr omicverse-rebuildr Public

    A reference-driven protocol for porting R / Bioconductor packages to pure-Python py-<pkg> standalones with class-aware numerical parity gates and verifier-guided acceleration.

    Python 10 1

Repositories

Showing 10 of 99 repositories
  • omicos Public

    omicOS 更新记录 / release notes (docs only — omicOS is a closed-source product)

    omicverse/omicos's past year of commit activity
    3 0 1 0 Updated Sep 11, 2026
  • omicverse-pages Public

    Static documentation site for omicverse

    omicverse/omicverse-pages's past year of commit activity
    Jupyter Notebook 1 1 0 0 Updated Sep 5, 2026
  • omicverse Public

    A python library for multi omics included bulk, single cell and spatial RNA-seq analysis.

    omicverse/omicverse's past year of commit activity
    Python 1,194 GPL-3.0 147 8 6 Updated Sep 5, 2026
  • luria-aido Public

    A shared-latent cell world model for K-562 over frozen single-modality encoders, shipped with the controls that say which legs work

    omicverse/luria-aido's past year of commit activity
    Python 0 MIT 0 0 0 Updated Sep 1, 2026
  • matverse Public

    A materials analysis ecosystem on the AnnData substrate

    omicverse/matverse's past year of commit activity
    Jupyter Notebook 1 MIT 0 0 0 Updated Aug 29, 2026
  • dsh-omicos Public

    Run OmicVerse/OmicOS bioinformatics analyses in a persistent Python kernel from inside DeepSeek Harness (dsh), with capability-catalog search and an account tab.

    omicverse/dsh-omicos's past year of commit activity
    TypeScript 2 GPL-3.0 0 0 0 Updated Aug 17, 2026
  • omicverse-tutorials Public

    OmicVerse and OmicClaw Tutorials

    omicverse/omicverse-tutorials's past year of commit activity
    Jupyter Notebook 6 5 0 1 Updated Jul 29, 2026
  • omicverse-rebuildr Public

    A reference-driven protocol for porting R / Bioconductor packages to pure-Python py-<pkg> standalones with class-aware numerical parity gates and verifier-guided acceleration.

    omicverse/omicverse-rebuildr's past year of commit activity
    Python 10 MIT 1 0 1 Updated Jul 28, 2026
  • py-nichede Public

    Pure-Python Niche-DE: niche-differential gene expression and context-dependent cell-cell interactions in spatial transcriptomics. Port of the R package nicheDE (Genome Biology 2024).

    omicverse/py-nichede's past year of commit activity
    Python 0 MIT 0 0 0 Updated Jul 28, 2026
  • py-spatialecotyper Public

    Pure-Python port of the R package SpatialEcoTyper (Zhang et al., Nature 2026): recurrent multicellular spatial ecotypes from single-cell spatial transcriptomics. Validated function-by-function against R 4.4.3 / Seurat 5.4.0.

    omicverse/py-spatialecotyper's past year of commit activity
    Python 2 GPL-3.0 0 0 0 Updated Jul 28, 2026

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